Gold SPR Therapy?

Advanced GOLD SPR (surface plasmon resonance) Near-infrared THERAPY

Historical Artifacts of SPR (Surface Plasmon Resonance)

The Lycurgus Cup (Rome, AD 4th)

The glass contains tiny amounts of gold and silver particles inducing SPR phenomena.

Physicochemical Properties of Gold Nanoparticles (AuNPs)-The surface plasmon effect


AuNPs are stable (inert) and non-toxic.

AuNPs can be used in a variety of applications in biomedical fields.

Chem Asian J. 2021, 16, 720 –742
Chem Asian J. 2021, 16, 720 –742

Surface plasmon resonance (SPR) is a crucial novel optical phenomenon possessed by plasmonic Gold nanoparticles (AuNPs), which are produced by electromagnetic radiations whose electrical constituents cause the excitation of free electrons (surface electrons) in metal.

The electronic oscillation of surface electrons results in a charge separation, which in turn produces dipole oscillation that works parallel to the direction of the electric field of the electromagnetic waves. The frequency (specific) at which the amplitude of the oscillation is maximum is called SPR frequency.

The band intensity of the SPR band is greatly affected by those factors, which also affect the surface’s electron charge density, such as surface morphology, composition, dielectric environment, metal type, and particle size. In the SPR phenomenon, the collective oscillation of electrons, due to interaction between light and surface electrons, has two modes: surface plasmon–polarization (SPP) and localized surface plasmon resonance (LSPR).

AuNPs are stable (inert) and non-toxic in a wide variety of environments with controllable optoelectrical properties. Owing to these benefits, AuNPs can be used in a variety of applications ranging from the environmental and energy sectors to biomedical fields.

Gold Cloud PAR, is based on Gold Nanoparticles Near-infrared SPR (surface plasmon resonance) technology. Gold Cloud PAR is a specially developed skin problem care solution which is an advanced gold therapy that is modified from gold PTT (photothermal therapy).RADKIN introducing GOLD CLOUD PAR based on Gold Nanoparticles Near-infrared SPR (surface plasmon resonance), the product optimized for energy devices using various lights, laser, plasma, and IPL.


Numerous free electrons exist inside the metal, which is a conductor. Since free electrons are not bound to metal atoms, they can easily respond to specific external stimuli. In particular, when a metal becomes nano-sized, a surface plasmon resonance characteristic appears due to the behavior of such free electrons and thus has unique optical properties. Surface plasmon resonance refers to a phenomenon in which free electrons on the metal surface collectively vibrate due to resonance with an electromagnetic field of specific light energy when light is incident between the surface of a metal nanoparticle, which is a conductor, and a dielectric such as air or water. Since the frequency of surface plasmon resonance varies depending on the size or shape of the metal nanoparticles, the dispersed solvent, etc., they can be adjusted and applied to applications using light of various wavelengths.

Gold nanoparticles (AuNPs) have been widely studied and applied in the field of tumor diagnosis and treatment because of their special fundamental properties.

Gold Cloud PAR is optimized for devices using various lights, laser, plasma, and IPL.

Schematic of plasmon oscillation for a sphere, showing the displacement of the conduction electron charge cloud relative to the nuclei.

J. Phys. Chem. B, 2003, 107, 668-677

E: electric, e: electron

Device application
Diode Laser, Fractional Laser, Laser toning

Acne, pigment, wrinkle

Applications of Gold Nanoparticles surface plasmon resonance, SPR

The SPR is an optical- electrical phenomenon that due to a charge density oscillation at the interface between a dielectric media and a metal


-Metal layer: Nano Gold

-Dielectric media: Light and frequency

Device application
Plasma Frequency
Acne, pigment

Device application
Plasma Frequency
Acne, pigment

Device application
Device application

Gold Cloud PAR-GOLD NANOPARTICLES SPR (surface plasmon resonance) THERAPY

Specially developed Gold Cloud PAR reduces skin inflammation, resulting strengthens skin barrier, improves skin tone, wrinkles, resilience, and pores with various skin resurfacing and skin brightening agents which are combined with ‘colloidal gold, colloidal platinum, and modified ethosomal carrier system which is exchanged alcohol to diol’ for activating plasmon resonance of skin surface and enhancing the skin penetration of skin cell nutritional and therapeutic concoction.

The point of GOLD SPR THERAPY is based on surface plasmon resonance of gold nanoparticles with device energy.

Gold and active ingredients capsulation system: Modified ethosome

Modified Ethosome

Ethosomal systems are modified from liposomes and are novel lipid vesicular carriers containing a relatively high percentage of ethanol to enhance capsule stability.

GOLD Cloud PAR’s special carrier system is a ‘Modified ethosome’ which is developed and modified capsule from ethosome, especially the alcohol was replaced to propanediol and combined with colloidal platinum and colloidal gold for specific reaction of surface plasmon resonance with energy device.

This carrier is specially designed for the efficient delivery of therapeutic agents with different physicochemical properties into deep skin layers and across the skin.

Capsulation technology

Comparison of classical ethosomes, binary ethosomes, transethosomes, and Modified Ethosomes in their initial suspension form