Specially designed ACCB Skin and Hair are based on an advanced stem cell technology with biomimetic peptides, antioxidants, and nutriment concoction for restoring skin and hair cells that were affected by the aging process of internal and external factors.
Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) have been suggested to promote tissue repair and have been used for tissue engineering in numerous studies. Not only can their multiple lineages replace aged or damaged cells, but their secretory factors can enhance tissue repair efficiency.
PATENT, W O 2017/123022
UCB-MSCs provide a high amount of growth factors
Stem cell-derived exosomes containing a high amount of growth factors
The protein expression level of EGF (epidermal growth factor), FGF (fibroblast growth factor), VEGF (vascular endothelial growth factor), TGF (transforming growth factor ), PDGF (platelet-derived growth factor), HGF (hepatocyte growth factor) was tested in the conditioned media of UCB, AD (adipose), and BM (bone marrow), Result shows the UCB-MSC exosome contains a higher level of growth factors compare with the exosome of AD and BM.
GROWTH FACTOR’s heat stability
ACCB SKIN & HAIR combine the protein heat stabilizing technology, which is a modified spherosome.
We combined modified spherosome technology in ACCB which is a kind of drug delivery system, and it was developed by modification of oleosome and cubosome for increasing heat-stability of proteins in ACCB.
Promotes ECMs gene expression
Use UCB-MSCs to determine the effects of both stem cells and their paracrine factors on reacquisition of hDPC (human dermal papilla cells) conduction ability to induce hair growth and to provide an effective therapeutic strategy for alopecia
UCB-MSCs promote hair follicle cycling, morphogenesis in vivo
hUCB-MSCs promoted the telogen-anagen transition, in particular, hair follicles that were treated with UCB-MSCs were transformed from the telogen phase to the early-and middle -anagen phases at 6 weeks.